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UCM05
CAS No. 1094451-90-7
UCM05( —— )
Catalog No. M33764 CAS No. 1094451-90-7
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including cell lines resistant to anti-HER2 drugs .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 78 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 275 | In Stock |
|
| 50MG | 423 | In Stock |
|
| 100MG | 625 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUCM05
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NoteResearch use only, not for human use.
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Brief DescriptionUCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including cell lines resistant to anti-HER2 drugs .
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DescriptionUCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetFatty Acid Synthase
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RecptorFatty Acid Synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number1094451-90-7
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Formula Weight464.38
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Molecular FormulaC24H16O10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (215.34 mM; Ultrasonic )
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SMILESOc1cc(cc(O)c1O)C(=O)Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c2ccccc2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Teresa Puig, et al. A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. Breast Cancer Res. 2011;13(6):R131.?
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