Muraglitazar( —— )

Catalog No. M33747 CAS No. 331741-94-7

Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Muraglitazar
Note

Research use only, not for human use.
Brief Description

Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.
Description

Muraglitazar is a PPAR α/γ dual agonist for the research of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα (EC50 = 320 nM) and PPARγ(EC50 = 110 nM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

PPAR
Recptor

PPAR
Research Area

——
Indication

——

Chemical Information

CAS Number

331741-94-7
Formula Weight

516.54
Molecular Formula

C29H28N2O7
Purity

>98% (HPLC)
Solubility

——
SMILES

C(COC1=CC=C(CN(C(OC2=CC=C(OC)C=C2)=O)CC(O)=O)C=C1)C=3N=C(OC3C)C4=CC=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Buse JB, Rubin CJ, Frederich R, et al. Muraglitazar, a dual (alpha/gamma) PPAR activator: a randomized, double-blind, placebo-controlled, 24-week monotherapy trial in adult patients with type 2 diabetes. Clin Ther. 2005;27(8):1181-1195. ?

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