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Pyrithioxin dihydrochloride
CAS No. 10049-83-9
Pyrithioxin dihydrochloride( —— )
Catalog No. M33686 CAS No. 10049-83-9
Pyrithioxin dihydrochloride (Pyrithioxine HCl) has anti-nociceptive and anti-allodynic effects, can promote the metabolism of glucose and amino acids in the brain, improve systemic assimilation, and can be used to study neurological diseases such as atherosclerosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 29 | Get Quote |
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| 100MG | 43 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePyrithioxin dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPyrithioxin dihydrochloride (Pyrithioxine HCl) has anti-nociceptive and anti-allodynic effects, can promote the metabolism of glucose and amino acids in the brain, improve systemic assimilation, and can be used to study neurological diseases such as atherosclerosis.
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DescriptionPyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number10049-83-9
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Formula Weight441.39
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Molecular FormulaC16H22Cl2N2O4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 66.67 mg/mL (151.05 mM; Ultrasonic )H2O : 50 mg/mL (113.28 mM; Ultrasonic)
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SMILESOC1=C(CO)C(CSSCC2=CN=C(C)C(O)=C2CO)=CN=C1C.Cl.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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7α,25-Dihydroxychole...
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM).
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L-Homoserine
Homoserine is a more reactive variant of the amino acid serine. In this variant the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer to its own carboxyl group allowing it to chemically react to form a five-membered ring.
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L-Kynurenine
L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
