Biotin-PEG8-amine

CAS No. 2183447-27-8

Biotin-PEG8-amine( —— )

Catalog No. M33544 CAS No. 2183447-27-8

Biotin-PEG8-amine is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Biotin-PEG8-amine
  • Note
    Research use only, not for human use.
  • Brief Description
    Biotin-PEG8-amine is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
  • Description
    Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PROTACs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2183447-27-8
  • Formula Weight
    638.81
  • Molecular Formula
    C28H54N4O10S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.?
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