TAMRA-PEG3-Azide

CAS No. 1228100-59-1

TAMRA-PEG3-Azide( —— )

Catalog No. M33506 CAS No. 1228100-59-1

TAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TAMRA-PEG3-Azide
  • Note
    Research use only, not for human use.
  • Brief Description
    TAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm.
  • Description
    TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1228100-59-1
  • Formula Weight
    630.69
  • Molecular Formula
    C33H38N6O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Methanol : 12.5 mg/mL (19.82 mM; Ultrasonic)
  • SMILES
    [N-]=[N+]=NCCOCCOCCOCCNC(=O)C=1C=CC(=C(C1)C(=O)[O-])C=2C=3C=CC(=CC3[O+]=C4C=C(C=CC42)N(C)C)N(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
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