Home - Products - GPCR/G Protein - Calcium Channel - Sipatrigine

Sipatrigine

CAS No. 130800-90-7

Sipatrigine( —— )

Catalog No. M33499 CAS No. 130800-90-7

Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	223	In Stock
5MG	202	In Stock
10MG	302	In Stock
25MG	506	In Stock
50MG	714	In Stock
100MG	1004	In Stock
200MG	1349	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Sipatrigine
Note

Research use only, not for human use.
Brief Description

Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
Description

Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel | Potassium Channel | Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

130800-90-7
Formula Weight

372.68
Molecular Formula

C15H16Cl3N5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (134.16 mM; Ultrasonic )
SMILES

CN1CCN(CC1)c1ncc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

2-Nitrobenzoic acid

2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.
Flosatidil

Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases, and can be used in the study of angina pectoris.
Argiprestocin

Vasopressin, ?also called?antidiuretic hormone?that plays a key role in maintaining?osmolality. It is a neurohypophysial hormone found in most mammals.

Sign In Join Free