Cart
sales@molnova.com
Sipatrigine
CAS No. 130800-90-7
Sipatrigine( —— )
Catalog No. M33499 CAS No. 130800-90-7
Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 202 | In Stock |
|
| 10MG | 302 | In Stock |
|
| 25MG | 506 | In Stock |
|
| 50MG | 714 | In Stock |
|
| 100MG | 1004 | In Stock |
|
| 200MG | 1349 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSipatrigine
-
NoteResearch use only, not for human use.
-
Brief DescriptionSipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
-
DescriptionSipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorCalcium Channel | Potassium Channel | Sodium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number130800-90-7
-
Formula Weight372.68
-
Molecular FormulaC15H16Cl3N5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (134.16 mM; Ultrasonic )
-
SMILESCN1CCN(CC1)c1ncc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.?
molnova catalog
related products
-
Cinacalcet metabolit...
Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.
-
Z-944
Z-944 is a potent, highly selective and oral T-type calcium channel blocker with IC50 of 50-160 nM for human Cav3.1, Cav3.2, and Cav3.3 channels.
-
Tamolarizine
Tamolarizine (Tamolarizine free base) free base is a novel calcium antagonist.
