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Lonapalene
CAS No. 91431-42-4
Lonapalene( —— )
Catalog No. M33486 CAS No. 91431-42-4
Lonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 335 | In Stock |
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| 2MG | 163 | In Stock |
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| 5MG | 307 | In Stock |
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| 10MG | 448 | In Stock |
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| 25MG | 677 | In Stock |
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| 50MG | 886 | In Stock |
|
| 100MG | 1190 | In Stock |
|
| 200MG | 1609 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLonapalene
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NoteResearch use only, not for human use.
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Brief DescriptionLonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.
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DescriptionLonapalene (RS4317) is a topically effective 5-lipoxygenase (5-LO) inhibitor.
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In VitroLonapalene (RS4317) may be useful in the treatment of psoriasis, and that leukotriene B4 is a relevant mediator of the pathology of this disease.
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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RecptorLipoxygenase
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Research Area——
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Indication——
Chemical Information
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CAS Number91431-42-4
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Formula Weight338.74
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Molecular FormulaC16H15ClO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (295.21 mM; Ultrasonic )
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SMILESCOc1c(OC)c(OC(C)=O)c2cc(Cl)ccc2c1OC(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Black AK, et al. Pharmacologic and clinical effects of lonapalene (RS 43179), a 5-lipoxygenase inhibitor, in psoriasis. J Invest Dermatol. 1990 Jul;95(1):50-4.?
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