LY341495( —— )

Catalog No. M33415 CAS No. 201943-63-7

LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used for the study of neurological disorders.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	189	In Stock
2MG	59	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

LY341495
Note

Research use only, not for human use.
Brief Description

LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used for the study of neurological disorders.
Description

LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM,14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Neuroscience
Target

GluR
Recptor

GluR
Research Area

——
Indication

——

Chemical Information

CAS Number

201943-63-7
Formula Weight

353.37
Molecular Formula

C20H19NO5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 6 mg/mL (16.98 mM; Ultrasonic )
SMILES

N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pitsikas N, et al. The metabotropic glutamate 2/3 receptor antagonist LY341495 differentially affects recognition memory in rats. Behav Brain Res. 2012 May 1;230(2):374-9.?

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