Hexane-1,6-diyldiphosphonic acid( —— )

Catalog No. M33381 CAS No. 4721-22-6

Hexane-1,6-diyldiphosphonic acid (1,6-Hexanebisphosphonic acid) is a PROTAC linker based on the alkyl chain.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Hexane-1,6-diyldiphosphonic acid
Note

Research use only, not for human use.
Brief Description

Hexane-1,6-diyldiphosphonic acid (1,6-Hexanebisphosphonic acid) is a PROTAC linker based on the alkyl chain.
Description

Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

PROTAC
Recptor

PROTAC Linker
Research Area

——
Indication

——

Chemical Information

CAS Number

4721-22-6
Formula Weight

246.14
Molecular Formula

C6H16O6P2
Purity

>98% (HPLC)
Solubility

——
SMILES

C(P(=O)(O)O)CCCCCP(=O)(O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?

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