Cart
sales@molnova.com
EGNHS
CAS No. 70539-42-3
EGNHS( —— )
Catalog No. M33347 CAS No. 70539-42-3
EGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 38 | Get Quote |
|
| 100MG | 59 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameEGNHS
-
NoteResearch use only, not for human use.
-
Brief DescriptionEGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
-
DescriptionEGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPROTAC Linker
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number70539-42-3
-
Formula Weight456.36
-
Molecular FormulaC18H20N2O12
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (219.13 mM; Ultrasonic )H2O : ≥ 4.17 mg/mL (9.14 mM)
-
SMILESOCC(=O)OC(=O)CC(N1C(=O)CCC1=O)C(=O)OCCOC(=O)C(CC(O)=O)N1C(=O)CCC1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
-
ARV-771
ARV-771, a small-molecule pan-BET degrader based on proteolysis-targeting chimera (PROTAC) technology, demonstrates dramatically improved efficacy in cellular models of CRPC as compared with BET inhibition.
-
Alkynyl Stearic Acid
Alkynyl Stearic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
TCO-NHS ester
TCO-NHS ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.
