EGNHS
CAS No. 70539-42-3
EGNHS( —— )
Catalog No. M33347 CAS No. 70539-42-3
EGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 38 | In Stock |
|
| 100MG | 61 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEGNHS
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NoteResearch use only, not for human use.
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Brief DescriptionEGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionEGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number70539-42-3
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Formula Weight456.36
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Molecular FormulaC18H20N2O12
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (219.13 mM; Ultrasonic )H2O : ≥ 4.17 mg/mL (9.14 mM)
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SMILESOCC(=O)OC(=O)CC(N1C(=O)CCC1=O)C(=O)OCCOC(=O)C(CC(O)=O)N1C(=O)CCC1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MT-802
MT-802 (MT802) is a potent BTK PROTAC that induces degradation of both wild-type and C481S mutant BTK (DC50=9.1 nM).
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NH2-C2-NH-Boc
NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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5-Ethynyl-2-deoxyuri...
5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.
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