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Home - Products - Metabolic Enzyme/Protease - Phospholipase - CCT129957

CCT129957

CAS No. 883098-58-6

CCT129957( —— )

Catalog No. M33309 CAS No. 883098-58-6

CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 85 In Stock
10MG 128 In Stock
25MG 233 In Stock
50MG 341 In Stock
100MG 513 In Stock
200MG Get Quote In Stock
500MG 1088 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    CCT129957
  • Note
    Research use only, not for human use.
  • Brief Description
    CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
  • Description
    CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca2+ release in squamous carcinoma cells at ~15 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phospholipase
  • Recptor
    Phospholipase | Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    883098-58-6
  • Formula Weight
    309.32
  • Molecular Formula
    C17H15N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (323.29 mM; Ultrasonic )
  • SMILES
    [O-][N+](=O)c1cccc2cc([nH]c12)C(=O)NCCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Reynisson J, et al. The identification of novel PLC-gamma inhibitors using virtual high throughput screening. Bioorg Med Chem. 2009 Apr 15;17(8):3169-76.?
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