Virginiamycin S1

CAS No. 23152-29-6

Virginiamycin S1( —— )

Catalog No. M33164 CAS No. 23152-29-6

Virginiamycin S1 is a streptozotocin B antibiotic produced by Streptomyces verticillioides, which has antibacterial activity by inhibiting bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Virginiamycin S1
  • Note
    Research use only, not for human use.
  • Brief Description
    Virginiamycin S1 is a streptozotocin B antibiotic produced by Streptomyces verticillioides, which has antibacterial activity by inhibiting bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation.
  • Description
    Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Antibiotic | Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    23152-29-6
  • Formula Weight
    823.89
  • Molecular Formula
    C43H49N7O10
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1N2[C@](C(=O)N[C@H](C(=O)O[C@H](C)[C@H](NC(=O)C3=C(O)C=CC=N3)C(=O)N[C@H](CC)C(=O)N4[C@](C(=O)N(C)[C@H]1CC5=CC=CC=C5)(CCC4)[H])C6=CC=CC=C6)(CC(=O)CC2)[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ningsih F, et al. VisG is essential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine.Microbiology. 2011 Nov;157(Pt 11):3213-20.?
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