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Temiverine hydrochloride

CAS No. 136529-33-4

Temiverine hydrochloride( —— )

Catalog No. M33143 CAS No. 136529-33-4

Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Temiverine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.
  • Description
    Temiverine hydrochloride is a synthesized agent that is expected to have anticholinergic action. Temiverine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    Atropine (1 nM to 1 μM), Oxybutynin (10 nM to 10 μM), Temiverine (10 nM to 10 μM), and RCC-36 (10 nM to 1 μM) cause a parallel shift to the right of the concentration-response curves to acetylcholine stimulation.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    136529-33-4
  • Formula Weight
    422
  • Molecular Formula
    C24H36ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.O=C(OC(C#CCN(CC)CC)(C)C)C(O)(C=1C=CC=CC1)C2CCCCC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kikukawa H, et al.Pharmacologic actions of temiverine (p-INN) and its active metabolite, RCC-36, on isolated human urinary bladder muscle. Int J Urol. 1998 May;5(3):268-75.?
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