Cart
sales@molnova.com
ORM-10103
CAS No. 488847-28-5
ORM-10103( —— )
Catalog No. M33047 CAS No. 488847-28-5
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 87 | In Stock |
|
| 5MG | 79 | In Stock |
|
| 10MG | 130 | In Stock |
|
| 25MG | 277 | In Stock |
|
| 50MG | 436 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | 799 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameORM-10103
-
NoteResearch use only, not for human use.
-
Brief DescriptionORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).
-
DescriptionORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorCalcium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number488847-28-5
-
Formula Weight348.35
-
Molecular FormulaC20H16N2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (717.67 mM; Ultrasonic )
-
SMILES[O-][N+](=O)c1ccc(Oc2ccc3OC(CCc3c2)c2ccccc2)nc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jost N, et al. ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart. Br J Pharmacol. 2013 Oct;170(4):768-78.?
molnova catalog
related products
-
ω-Agatoxin TK
Selective blocker of CaV2.1 P/Q-type calcium channels.
-
Verapamil hydrochlor...
Verapamil Hcl is an L-type calcium channel blocker of the phenylalkylamine class.
-
PD173212
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice.
