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Home - Products - Metabolic Enzyme/Protease - P450 - 7-BFC

7-BFC

CAS No. 220001-53-6

7-BFC( —— )

Catalog No. M32980 CAS No. 220001-53-6

7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that serves as a biomarker for cytochrome P 450 and can be used to study CYP isoforms and cytochrome P 450 metabolism.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 61 In Stock
25MG 128 In Stock
50MG 198 In Stock
100MG 323 In Stock
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Biological Information

  • Product Name
    7-BFC
  • Note
    Research use only, not for human use.
  • Brief Description
    7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that serves as a biomarker for cytochrome P 450 and can be used to study CYP isoforms and cytochrome P 450 metabolism.
  • Description
    7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    P450
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    220001-53-6
  • Formula Weight
    320.26
  • Molecular Formula
    C17H11F3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)c1cc(=O)oc2cc(OCc3ccccc3)ccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. A B Renwick, et al.? Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms. Xenobiotica. 2000 Oct;30(10):955-69.?
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