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IL-17A antagonist 1
CAS No. 2205034-18-8
IL-17A antagonist 1( —— )
Catalog No. M32964 CAS No. 2205034-18-8
IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
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Biological Information
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Product NameIL-17A antagonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionIL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.
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DescriptionIL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0.66 μM and an IC50 of 1.14 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetIL Receptor
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RecptorIL Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2205034-18-8
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Formula Weight604.71
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Molecular FormulaC33H41FN6O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 41.67 mg/mL (68.91 mM; Ultrasonic (<60°C)
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SMILESCN(C)C(=O)CC1(CC(=O)NCCc2ccc(NC(=O)[C@H](Cc3ccccc3F)NC(=O)c3ccnn3C)cc2)CCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu S, et al. Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep. 2016 Aug 16;6:30859.?
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