Gly-β-MCA( —— )

Catalog No. M32942 CAS No. 66225-78-3

Gly-β-MCA is an orally bioactive, enteroselective and potent inhibitor of the farnesoid X receptor (FXR), a bile acid, used in the study of obesity and diabetes.

Purity : >98% (HPLC)

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Biological Information

Product Name

Gly-β-MCA
Note

Research use only, not for human use.
Brief Description

Gly-β-MCA is an orally bioactive, enteroselective and potent inhibitor of the farnesoid X receptor (FXR), a bile acid, used in the study of obesity and diabetes.
Description

Gly-β-MCA, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

FXR
Recptor

FXR
Research Area

——
Indication

——

Chemical Information

CAS Number

66225-78-3
Formula Weight

465.62
Molecular Formula

C26H43NO6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (214.77 mM; Ultrasonic ) H2O : < 0.1 mg/mL (insoluble)
SMILES

C[C@H](CCC(=O)NCC(O)=O)C1CCC2C3[C@@H](O)[C@@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jiang C, et al. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun. 2015 Dec 15;6:10166.?

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