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Catechin 7-O-beta-D-glucopyranoside

CAS No. 65597-47-9

Catechin 7-O-beta-D-glucopyranoside( —— )

Catalog No. M32494 CAS No. 65597-47-9

Catechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 211 In Stock
25MG 356 In Stock
50MG 513 In Stock
100MG 732 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Catechin 7-O-beta-D-glucopyranoside
  • Note
    Research use only, not for human use.
  • Brief Description
    Catechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity.
  • Description
    Catechin 7-O-beta-D-glucopyranoside has intestinal anti-inflammatory activity. Catechin 7-O-beta-D-glucopyranoside has a protective effect against STZ-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction.Catechin 7-O-β-D-glucopyranoside has strong inhibitory activity against α-amylase and α-glucosidase.Catechin 7-O-β-D-glucopyranoside has the activity of inhibiting protein glycation.
  • In Vitro
    Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction. Western Blot Analysis Cell Line:RINm5F rat pancreatic β-cells Concentration:10 μg/mL Incubation Time:24 hours Result:Increased the MnSOD level attenuated by Streptozotocin treatment.Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
  • In Vivo
    Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN.Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis. Animal Model:Mice injected with LPS/D-GalN Dosage:10 mg/kg Administration:Intraperitoneal injection; 10 mg/kg; once Result:Showed 80% LPS/DGalN-induced lethality in mice.Animal Model:Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis Dosage:10 mg/kg Administration:Oral administration; 10 mg/kg; once daily; 7 days Result:Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats.Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65597-47-9
  • Formula Weight
    452.4
  • Molecular Formula
    C21H24O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO, Pyridine, Methanol, Ethanol, etc.
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cell Biochem Funct . 2010 Dec 2;28(8):651-660.
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