Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine.

δ-Amyrenone has anti-inflammatory effects and is a pentacyclic triterpenoid compound of linear streptomyces.

Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor GABAA receptor and the inward-rectifier potassium ion channel.