Aminomalonic acid (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. The presence of Ama has important biological implications because the malonic acid moiety potentially imparts calcium binding properties to protein.

MCPA（Krezone） is a highly effective phenoxy herbicide. Use of MCPA would have impacts on nearby water and soil resources.

Phosphoenolpyruvic acid monopotassium salt is involved in glycolysis and gluconeogeneis. In glycolysis PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.