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Protopine hydrochloride
CAS No. 6164-47-2
Protopine hydrochloride( —— )
Catalog No. M30941 CAS No. 6164-47-2
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1413 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameProtopine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionProtopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.
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DescriptionProtopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the heterotypic cell adhesion between MDA-MB-231 cells, and human umbilical vein endothelial cells by changing the expression of adhesive factors.
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In VitroWestern Blot Analysis Cell Line:HepG2, Huh7 Concentration:10, 20, 40 μM Incubation Time:24 h Result:Induced the cleavage of caspase-3 and caspase-9.Decreased Bcl-2 and Bcl-xl level.Induced the release of mitochondrial protein cytochrome c into the cytosol.
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In VivoAnimal Model:5-hydroxy-DL-tryptophan (5-HTP)-induced mice model Dosage:5, 10, 20 mg/kg Administration:i.p.Result:Increased the number of 5-HTP-induced head twitch response (HTR).Decreased the immobility time tested in the Tail suspension test (TST).
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number6164-47-2
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Formula Weight389.83
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Molecular FormulaC20H20ClNO5
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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