Buddlejasaponin IV( —— )

Catalog No. M30940 CAS No. 139523-30-1

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Product Name

Buddlejasaponin IV
Note

Research use only, not for human use.
Brief Description

Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation.
Description

Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation.
In Vitro

Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes.Buddlejasaponin IV (BS-IV) exhibits anti-inflammatory effect of through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-κB inactivation.
In Vivo

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