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R-IMPP
CAS No. 2133832-83-2
R-IMPP( —— )
Catalog No. M17432 CAS No. 2133832-83-2
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 69 | Get Quote |
|
| 2MG | 51 | Get Quote |
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| 5MG | 81 | Get Quote |
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| 10MG | 143 | Get Quote |
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| 25MG | 296 | Get Quote |
|
| 50MG | 516 | Get Quote |
|
| 100MG | 742 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameR-IMPP
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NoteResearch use only, not for human use.
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Brief DescriptionR-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
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DescriptionR-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPCSK9
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number2133832-83-2
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Formula Weight389.21
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Molecular FormulaC24H27N3O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 41 mg/mL; 105.27 mM
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SMILESCOC1=CC=C(CCC(N(C2=C(C=CC=C3)C3=CC=N2)[C@H]4CNCCC4)=O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371.
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