[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P( —— )

Catalog No. M30808 CAS No. 96736-12-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
Note

Research use only, not for human use.
Brief Description

Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
Description

Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
In Vitro

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In Vivo

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Synonyms

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Pathway

MAPK/ERK Signaling
Target

JNK
Recptor

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Research Area

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Indication

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CAS Number

96736-12-8
Formula Weight

1516.85
Molecular Formula

C79H109N19O12
Purity

>98% (HPLC)
Solubility

water:1 mg/mL
SMILES

[H]N[C@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
Chemical Name

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