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[Sar9] Substance P
CAS No. 77128-75-7
[Sar9] Substance P( —— )
Catalog No. M30560 CAS No. 77128-75-7
[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name[Sar9] Substance P
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NoteResearch use only, not for human use.
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Brief Description[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
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Description[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorNeurokinin (NK)-1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number77128-75-7
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Formula Weight1361.66
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Molecular FormulaC64H100N18O13S
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Purity>98% (HPLC)
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SolubilityIn Vitro:? H2O : ≥ 50 mg/mL (36.72 mM)
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SMILES——
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Chemical NameSequence:{Arg}{Pro}{Lys}{Pro}{Gln}{Gln}{Phe}{Phe}{SAR}{Leu}{Met}-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Lieberman DN, et al. Substance P enhances NMDA channel function in hippocampal dentate gyrus granule cells. J Neurophysiol. 1998 Jul;80(1):113-9.
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related products
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[Nle11]-Substance P
[Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.
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Substance P (1-9)
Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
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Vapreotide acetate
Vapreotide acetate is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).
