[Sar9] Substance P( —— )

Catalog No. M30560 CAS No. 77128-75-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

[Sar9] Substance P
Note

Research use only, not for human use.
Brief Description

[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Description

[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
In Vitro

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In Vivo

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Synonyms

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Pathway

GPCR/G Protein
Target

Neurokinin Receptor
Recptor

Neurokinin (NK)-1 receptor
Research Area

——
Indication

——

CAS Number

77128-75-7
Formula Weight

1361.66
Molecular Formula

C64H100N18O13S
Purity

>98% (HPLC)
Solubility

In Vitro:? H2O : ≥ 50 mg/mL (36.72 mM)
SMILES

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Chemical Name

Sequence:{Arg}{Pro}{Lys}{Pro}{Gln}{Gln}{Phe}{Phe}{SAR}{Leu}{Met}-NH2

Lieberman DN, et al. Substance P enhances NMDA channel function in hippocampal dentate gyrus granule cells. J Neurophysiol. 1998 Jul;80(1):113-9.

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