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Substance P (1-9)
CAS No. 57468-17-4
Substance P (1-9)( —— )
Catalog No. M30517 CAS No. 57468-17-4
Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 133 | Get Quote |
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| 10MG | 206 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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Biological Information
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Product NameSubstance P (1-9)
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NoteResearch use only, not for human use.
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Brief DescriptionSubstance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
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DescriptionSubstance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.(In Vitro):Substance P (1-9) is a nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder, but with no significant effects on bradykinin or SP-(6-11).
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In VitroSubstance P (1-9) is a nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder, but with no significant effects on bradykinin or SP-(6-11).
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number57468-17-4
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Formula Weight1104.26
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Molecular FormulaC52H77N15O12
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (22.64 mM)
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SMILES——
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Chemical NameSequence:Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Hemokinin 1 (human)
Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
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Neurokinin A(4-10)
Neurokinin A (4-10) is a tachykinin NK2 receptor agonist. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) was performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle.
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[Lys5,MeLeu9,Nle10]-...
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
