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Angiotensin III, human, mouse
CAS No. 13602-53-4
Angiotensin III, human, mouse( —— )
Catalog No. M30432 CAS No. 13602-53-4
Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
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| 25MG | 86 | In Stock |
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| 50MG | 142 | In Stock |
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| 100MG | 232 | In Stock |
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| 200MG | 349 | In Stock |
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Biological Information
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Product NameAngiotensin III, human, mouse
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NoteResearch use only, not for human use.
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Brief DescriptionAngiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
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DescriptionAngiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.(In Vitro):Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.(In Vivo):Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats.
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In VitroAngiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
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In VivoAngiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorIC50: 0.648 nM (AT2R), 21.1 nM (AT1R)
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Research Area——
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Indication——
Chemical Information
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CAS Number13602-53-4
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Formula Weight931.09
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Molecular FormulaC46H66N12O9
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (107.40 mM)
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SMILES——
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Chemical NameSequence:Arg-Val-Tyr-Ile-His-Pro-Phe
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Bosnyak S, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond). 2011 Oct;121(7):297-303.
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