Cart
sales@molnova.com
Urocortin III, mouse
CAS No. 357952-10-4
Urocortin III, mouse( —— )
Catalog No. M30348 CAS No. 357952-10-4
Mouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameUrocortin III, mouse
-
NoteResearch use only, not for human use.
-
Brief DescriptionMouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.
-
DescriptionMouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCRF Receptor
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number357952-10-4
-
Formula Weight4172.97
-
Molecular FormulaC186H312N52O52S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:{Phe}{Thr}{Leu}{Ser}{Leu}{Asp}{Val}{Pro}{Thr}{Asn}{Ile}{Met}{Asn}{Ile}{Leu}{Phe}{Asn}{Ile}{Asp}{Lys}{Ala}{Lys}{Asn}{Leu}{Arg}{Ala}{Lys}{Ala}{Ala}{Ala}{Asn}{Ala}{Gln}{Leu}{Met}{Ala}{Gln}{Ile}-NH2
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7570-5. Lewis K, et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.
molnova catalog
related products
-
Sauvagine
Corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.
-
CP 316311
CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression.
-
Antisauvagine-30
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells (pA2 = 8.49). Prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo.
