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Cyclic MKEY
CAS No. 934385-55-4
Cyclic MKEY( —— )
Catalog No. M30319 CAS No. 934385-55-4
MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCyclic MKEY
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NoteResearch use only, not for human use.
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Brief DescriptionMKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.
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DescriptionMKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCXCL4-CCL5 heterodimer formation
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Research Area——
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Indication——
Chemical Information
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CAS Number934385-55-4
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Formula Weight2532.89
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Molecular FormulaC113H174N28O34S2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Cys}{Lys}{Glu}{Tyr}{Phe}{Tyr}{Thr}{Ser}{Ser}{Lys}{Ser}{Ser}{Asn}{Leu}{Ala}{Val}{Val}{Phe}{Val}{Thr]
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615.
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