GPLGIAGQ
CAS No. 109053-09-0
GPLGIAGQ( —— )
Catalog No. M30234 CAS No. 109053-09-0
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGPLGIAGQ
-
NoteResearch use only, not for human use.
-
Brief DescriptionGPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.
-
DescriptionGPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. (In Vitro):GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.
-
In VitroGPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetMMP
-
RecptorMMP2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number109053-09-0
-
Formula Weight711.81
-
Molecular FormulaC31H53N9O10
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:{Gly}{Pro}{Leu}{Gly}{Ile}{Ala}{Gly}{Gln}
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Hou W, et al. MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy. ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1447-57.
molnova catalog
related products
-
CTS-1027
A potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14.
-
MMP-9-IN-7
Acetamide, N-[2-[(5-chloro-2 methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-inhibits pro-matrix metalloproteinase activation and can be used to prevent, treat or ameliorate MMP9 and/or MMP13-mediated syndromes.
-
BPHA
BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.
Cart
sales@molnova.com