GPLGIAGQ( —— )

Catalog No. M30234 CAS No. 109053-09-0

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

GPLGIAGQ
Note

Research use only, not for human use.
Brief Description

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.
Description

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. (In Vitro):GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.
In Vitro

GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

MMP
Recptor

MMP2
Research Area

——
Indication

——

Chemical Information

CAS Number

109053-09-0
Formula Weight

711.81
Molecular Formula

C31H53N9O10
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

Sequence:{Gly}{Pro}{Leu}{Gly}{Ile}{Ala}{Gly}{Gln}

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Hou W, et al. MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy. ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1447-57.

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