Parasin I( —— )

Catalog No. M30064 CAS No. 219552-69-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Parasin I
Note

Research use only, not for human use.
Brief Description

Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus).
Description

Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus).(In Vitro):Parasin I with comparable antimicrobial activities localized to the cell membrane and subsequently permeabilized the outer and cytoplasmic membranes. Parasin I and its active analogs show strong cytoplasmic membrane permeabilizing activity. Codon optimized parasin I fused with human lysozyme is expressed in Pichia pastoris, and has potent antibiotic activity.
In Vitro

Parasin I with comparable antimicrobial activities localized to the cell membrane and subsequently permeabilized the outer and cytoplasmic membranes. Parasin I and its active analogs show strong cytoplasmic membrane permeabilizing activity. Codon optimized parasin I fused with human lysozyme is expressed in Pichia pastoris, and has potent antibiotic activity.
In Vivo

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Synonyms

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Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

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Research Area

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Indication

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CAS Number

219552-69-9
Formula Weight

2000.31
Molecular Formula

C82H154N34O24
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

Sequence:Lys-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser

Koo YS, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008 Jul;29(7):1102-8.

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