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Ampicillin

CAS No. 69-53-4

Ampicillin( Aminobenzylpenicillin | Ampicillin acid | Principen | Amcill | Ampicilline )

Catalog No. M15659 CAS No. 69-53-4

Ampicillin is an orally active broad-spectrum antibiotic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ampicillin
  • Note
    Research use only, not for human use.
  • Brief Description
    Ampicillin is an orally active broad-spectrum antibiotic.
  • Description
    Ampicillin is an orally active broad-spectrum antibiotic.(In Vitro):Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL.(In Vivo):Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.
  • In Vitro
    Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL.
  • In Vivo
    Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.
  • Synonyms
    Aminobenzylpenicillin | Ampicillin acid | Principen | Amcill | Ampicilline
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    PBPs
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    69-53-4
  • Formula Weight
    349.4
  • Molecular Formula
    C16H19N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: > 10 mM
  • SMILES
    CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C
  • Chemical Name
    (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Babu E, et al. Jpn J Pharmacol. 2002 Jan;88(1):69-76.
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