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Neuropeptide FF
CAS No. 99566-27-5
Neuropeptide FF( NPFF )
Catalog No. M29773 CAS No. 99566-27-5
Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNeuropeptide FF
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NoteResearch use only, not for human use.
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Brief DescriptionEndogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
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DescriptionEndogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
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In Vitro——
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In Vivo——
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SynonymsNPFF
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PathwayGPCR/G Protein
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TargetNeuropeptide Y Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number99566-27-5
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Formula Weight1081.27
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Molecular FormulaC54H76N14O10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (92.48 mM)
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SMILES——
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Chemical NameSequence:{Phe}{Leu}{Phe}{Gln}{Pro}{Gln}{Arg}{Phe}-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Galanin (1-29) (rat,...
Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
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Neuropeptide SF (mou...
Neuropeptide FF receptor agonist (Ki values are 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). Potentiates the antinociceptive action of morphine in vivo and reverses the loss of morphine potency in tolerant animals. Also increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) (EC50 ~ 50 μM).
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CART (55-102) (human...
Cocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response.
