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Prosaikogenin G
CAS No. 99365-23-8
Prosaikogenin G( —— )
Catalog No. M29487 CAS No. 99365-23-8
Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 140 | In Stock |
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| 5MG | 242 | In Stock |
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| 10MG | 359 | In Stock |
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| 25MG | 595 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameProsaikogenin G
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NoteResearch use only, not for human use.
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Brief DescriptionProsaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial
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DescriptionProsaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial(In Vitro):Prosaikogenin G holds a protective effect on the kidney for their down-regulated activity to angiotensin II (1 μM)-induced rat mesangial cell line (MC) proliferation at contentration of 25 or 50 μM, and does not rendered injury to the normal MC .
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In VitroProsaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorRAAS
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Research Area——
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Indication——
Chemical Information
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CAS Number99365-23-8
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Formula Weight618.84
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Molecular FormulaC36H58O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (80.80 mM)
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SMILESC[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3C=C[C@]35OC[C@@]6(CCC(C)(C)C[C@@H]36)[C@H](O)C[C@@]45C)[C@]2(C)CO)[C@H](O)[C@@H](O)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Delapril?Hydrochlori...
Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid.
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Nitrosoglutathione
GSNO is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses.
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N-Acetyl-Ser-Asp-Lys...
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice.N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) is a specific substrate for the N-terminal site of ACE and increases 5-fold during ACE inhibitor therapy.??AcSDKP inhibited the proliferation of isolated cardiac fibroblasts (P<0.05) but significantly stimulated the proliferation of vascular smooth muscle cells.?
