Prosaikogenin G( —— )

Catalog No. M29487 CAS No. 99365-23-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Prosaikogenin G
Note

Research use only, not for human use.
Brief Description

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial
Description

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial(In Vitro):Prosaikogenin G holds a protective effect on the kidney for their down-regulated activity to angiotensin II (1 μM)-induced rat mesangial cell line (MC) proliferation at contentration of 25 or 50 μM, and does not rendered injury to the normal MC .
In Vitro

Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC.
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

RAAS
Recptor

RAAS
Research Area

——
Indication

——

CAS Number

99365-23-8
Formula Weight

618.84
Molecular Formula

C36H58O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (80.80 mM)
SMILES

C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3C=C[C@]35OC[C@@]6(CCC(C)(C)C[C@@H]36)[C@H](O)C[C@@]45C)[C@]2(C)CO)[C@H](O)[C@@H](O)[C@H]1O
Chemical Name

——