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Delapril?Hydrochloride
CAS No. 83435-67-0
Delapril?Hydrochloride( —— )
Catalog No. M16093 CAS No. 83435-67-0
Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 53 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 137 | In Stock |
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| 100MG | 183 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDelapril?Hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionDelapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid.
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DescriptionDelapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme (ACE), hence blocking angiotensin I to angiotensin II conversion.(In Vivo):Delapril (3 mg/kg; administered orally for 2 weeks) exerts potent ACE inhibitory activity in spontaneously hypertensive rat (SHR) .Delapril (1-10 mg/kg; orally) exerts a marked and long-lasting antihypertensive action in various experimental models of hypertension.
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In Vitro——
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In VivoDelapril (3 mg/kg; administered orally for 2 weeks) exerts potent ACE inhibitory activity in spontaneously hypertensive rat (SHR) .Delapril (1-10 mg/kg; orally) exerts a marked and long-lasting antihypertensive action in various experimental models of hypertension. Animal Model:SHR Dosage:3 mg/kg Administration:Administered orally; 2 weeks Result:Exerted potent ACE inhibitory activity.Animal Model:2-kidney, 1-clip hypertensive Rats, Dogs, and SHR Dosage:1-10 mg/kg.Administration:Oral Result:Exerted a marked and long-lasting antihypertensive action.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorACE
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Research Area——
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Indication——
Chemical Information
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CAS Number83435-67-0
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Formula Weight489
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Molecular FormulaC26H33ClN2O5
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESCCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N(CC(=O)O)C2CC3=CC=CC=C3C2.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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N-Acetyl-Ser-Asp-Lys...
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice.N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) is a specific substrate for the N-terminal site of ACE and increases 5-fold during ACE inhibitor therapy.??AcSDKP inhibited the proliferation of isolated cardiac fibroblasts (P<0.05) but significantly stimulated the proliferation of vascular smooth muscle cells.?
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ZD 7155 hydrochlorid...
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
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Benazepril hydrochlo...
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure.
