5-Hydroxy-7,8-dimethoxyflavanone

Research use only, not for human use.

5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.

5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.(In Vitro):5-Hydroxy-7,8-dimethoxyflavanone efficiently increased the susceptibility of CYP6AA3- and CYP6P7-expressing Spodoptera frugiperda (Sf9) cells to cypermethrin toxicity, due to inhibition effects on mosquito enzymes. 5-Hydroxy-7,8-dimethoxyflavanone significantly decreases TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells.

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Apoptosis

IL Receptor

IL Receptor

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113981-49-0

300.3

C17H16O5

>98% (HPLC)

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COc1cc(O)c2C(=O)C[C@H](Oc2c1OC)c1ccccc1

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(-20℃)

With Ice Pack

≥ 2 years