Isoforskolin( Coleonol B )

Catalog No. M29121 CAS No. 64657-21-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Isoforskolin
Note

Research use only, not for human use.
Brief Description

Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.
Description

Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.(In Vivo):Isoforskolin downregulats the transcription and expression of TNF-α and IL-6 induced by rBmpA in mice. Isoforskolin inhibits the symptoms of experimental Lyme arthritis.
In Vitro

Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA).
In Vivo

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Synonyms

Coleonol B
Pathway

Apoptosis
Target

IL Receptor
Recptor

IL Receptor
Research Area

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Indication

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CAS Number

64657-21-2
Formula Weight

410.507
Molecular Formula

C22H34O7
Purity

>98% (HPLC)
Solubility

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SMILES

CC(=O)O[C@@H]1[C@H](O)[C@@]2(C)O[C@](C)(CC(=O)[C@@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
Chemical Name

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