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Ayanin
CAS No. 572-32-7
Ayanin( —— )
Catalog No. M29095 CAS No. 572-32-7
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma. The IC50 value of Ayanin is 2.2microM for inhibiting interleukin IL-4 production from purified basophils. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for respiratory disease researches.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 345 | In Stock |
|
| 10MG | 511 | In Stock |
|
| 25MG | 812 | In Stock |
|
| 50MG | 1070 | In Stock |
|
| 100MG | 1442 | In Stock |
|
| 200MG | 1841 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAyanin
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NoteResearch use only, not for human use.
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Brief DescriptionAyanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma. The IC50 value of Ayanin is 2.2microM for inhibiting interleukin IL-4 production from purified basophils. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for respiratory disease researches.
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DescriptionAyanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma. The IC50 value of Ayanin is 2.2microM for inhibiting interleukin IL-4 production from purified basophils. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for respiratory disease researches.(In Vitro):Incubation of human leukemia cells with Ayanin diacetate induced G(2)-M phase cell cycle arrest and apoptosis which was prevented by the non-specific caspase inhibitor z-VAD-fmk and reduced by the overexpression of Bcl-x(L). Ayanin diacetate-induced cell death was found to be associated with: (i) loss of inner mitochondrial membrane potential, (ii) the release of cytochrome c, (iii) the activation of multiple caspases, (iv) cleavage of poly(ADP-ribose) polymerase and (v) the up-regulation of death receptors for TRAIL, DR4 and DR5. Moreover, the combined treatment with Ayanin diacetate and TRAIL amplified cell death, compared to single treatments.
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In VitroAyanin inhibits interleukin (IL)-4 production from purified basophils with an IC50 value of 2.2 μM.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetIL Receptor
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RecptorIL Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number572-32-7
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Formula Weight344.319
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Molecular FormulaC18H16O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (726.07 mM)
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SMILESCOc1cc(O)c2c(c1)oc(-c1ccc(OC)c(O)c1)c(OC)c2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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