Alpha-Amyrin( α-Amyrin | Viminalol | alpha-Amyrine | alpha-Amyrenol )

Catalog No. M29087 CAS No. 638-95-9

Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Alpha-Amyrin
Note

Research use only, not for human use.
Brief Description

Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.
Description

Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.(In Vitro):Alpha-Amyrin induces the proliferation of human keratinocytes by about 18%.
In Vitro

Cell Viability Assay Cell Line:C2C12 Concentration:1, 10 100 μM Incubation Time:24 h Result:Reduced cell viability at 100 μM.Western Blot Analysis Cell Line:C2C12 Concentration: 10 μM Incubation Time:24 h Result:Increased the mRNA and protein expression of PPARs, GLUT4 and FATP.
In Vivo

Animal Model:High-fructose diet (HFD)-induced metabolic syndrome in ratsDosage:50, 100, 200 mg/kg Administration:p.o.Result:Decreased systolic blood pressure, plasma glucose, total cholesterol, and plasma triglycerides.Attenuated hepatic oxidative stress as well as micro- and macrovesicular fatty changes in hepatocytes caused by HFD.Animal Model:Scopolamine-Induced Memory Impairment Mice Dosage:2 or 4 mg/kg Administration:p.o.Result:Increased the expression levels of phosphorylated extracellular signal-regulated kinase 1/2 (pERK) and phosphorylated glycogen synthase kinase-3β (pGSK-3β).
Synonyms

α-Amyrin | Viminalol | alpha-Amyrine | alpha-Amyrenol
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

P450
Research Area

——
Indication

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Chemical Information

CAS Number

638-95-9
Formula Weight

426.729
Molecular Formula

C30H50O
Purity

>98% (HPLC)
Solubility

In Vitro:?Methanol : 1 mg/mL (2.34 mM)
SMILES

[H][C@@]12[C@@H](C)[C@H](C)CC[C@]1(C)CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C
Chemical Name

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