3,4-O-Isopropylidene-shikimic acid

Research use only, not for human use.

3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.

3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.(In Vitro):3,4-O-Isopropylidene shikimic acid (ISA,1-100 micromol/L) effectively reduced PMN adhesion to TNF-alpha-induced HUVEC with the inhibitory rate from 17.2 % to 53.5 % and exerted no effect on PMN adhesion to normal HUVEC. Adhesion molecule ICAM-1 surface protein and mRNA expression induced by TNF-alpha (400 kU/L) were significantly inhibited by ISA. In addition, the cell viability of HUVEC was unchanged 48 h after treatment with ISA.

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3,4-O-Isopropylidene shikimic acid | 3,4-O-Isopropylidene-shikimic acid

Immunology/Inflammation

NOS

NOS

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183075-03-8

214.2

C10H14O5

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (466.81 mM)

CC(C)(O[C@H]1[C@@H](C2)O)O[C@@H]1C=C2C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years