1,2,3,6-Tetragalloylglucose( TeGG | 1,2,3,6-Tetra-O-galloyl-β-D-glucose )

Catalog No. M29063 CAS No. 79886-50-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

1,2,3,6-Tetragalloylglucose
Note

Research use only, not for human use.
Brief Description

1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
Description

1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).(In Vitro):The phenolic 1,2,3,6-Tetragalloylglucose (2), isolated from the stem-bark of Juglans mandshurica was evaluated for its antioxidative activity. The results showed that 1,2,3,6-Tetragalloylglucose exhibited strong scavenging activities against 1,1'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzenthiazoline-6-sulphonic) acid (ABTS(*+)), and superoxide radicals (O(2)(*-)), and also had a significant inhibitory effect on lipid peroxidation and low-density lipoprotein (LDL) oxidation.
In Vitro

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In Vivo

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Synonyms

TeGG | 1,2,3,6-Tetra-O-galloyl-β-D-glucose
Pathway

Metabolic Enzyme/Protease
Target

LDL
Recptor

LDL
Research Area

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Indication

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CAS Number

79886-50-3
Formula Weight

788.576
Molecular Formula

C34H28O22
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (126.81 mM)
SMILES

O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1
Chemical Name

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