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(E)-SI-2

CAS No. 380537-35-9

(E)-SI-2( —— )

Catalog No. M28929 CAS No. 380537-35-9

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	136	In Stock
5MG	134	In Stock
10MG	199	In Stock
25MG	316	In Stock
50MG	442	In Stock
100MG	593	In Stock
200MG	775	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

(E)-SI-2
Note

Research use only, not for human use.
Brief Description

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
Description

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

380537-35-9
Formula Weight

265.31
Molecular Formula

C15H15N5
Purity

>98% (HPLC)
Solubility

——
SMILES

CN1C2=CC=CC=C2N=C1N/N=C(C3=NC=CC=C3)\C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.By Wright, George E.; Xu, Wei-Chu From U.S. (2014), US 8796292 B2 20140805.

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