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6,6'-Dithiodinicotinic Acid
CAS No. 15658-35-2
6,6'-Dithiodinicotinic Acid( —— )
Catalog No. M28914 CAS No. 15658-35-2
6,6'-Dithiodinicotinic Acid is a non permeant thiol agent which affects several mitochondrial functions. In rat liver mitochondria, 6,6'-Dithiodinicotinic Acid inhibits only the Pi/OH- carrier; both 6,6'-Dithiodinicotinic Acid and n-butylmalonate are necessary to inhibit completely Pi entry.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 59 | In Stock |
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| 25MG | 92 | In Stock |
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| 50MG | 138 | In Stock |
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| 100MG | 193 | In Stock |
|
| 200MG | 291 | In Stock |
|
| 500MG | 490 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name6,6'-Dithiodinicotinic Acid
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NoteResearch use only, not for human use.
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Brief Description6,6'-Dithiodinicotinic Acid is a non permeant thiol agent which affects several mitochondrial functions. In rat liver mitochondria, 6,6'-Dithiodinicotinic Acid inhibits only the Pi/OH- carrier; both 6,6'-Dithiodinicotinic Acid and n-butylmalonate are necessary to inhibit completely Pi entry.
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Description6,6'-Dithiodinicotinic Acid is a non permeant thiol agent which affects several mitochondrial functions. In rat liver mitochondria, 6,6'-Dithiodinicotinic Acid inhibits only the Pi/OH- carrier; both 6,6'-Dithiodinicotinic Acid and n-butylmalonate are necessary to inhibit completely Pi entry.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorFerroptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number15658-35-2
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Formula Weight308.33
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Molecular FormulaC12H8N2O4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (405.41 mM)
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SMILESOC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chen X, et al. Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action. ACS Cent Sci. 2021 Jun 23;7(6):980-989.
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