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IRAK-4 protein kinase inhibitor 2

CAS No. 301675-24-1

IRAK-4 protein kinase inhibitor 2( —— )

Catalog No. M28816 CAS No. 301675-24-1

IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IRAK-4 protein kinase inhibitor 2
  • Note
    Research use only, not for human use.
  • Brief Description
    IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
  • Description
    IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).(In Vitro):IRAK-4 protein kinase inhibitor 2 inhibited IRAK-1 (IC50 <10 μM) as well.
  • In Vitro
    IRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of <10 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    IRAK
  • Recptor
    α1-adrenoceptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    301675-24-1
  • Formula Weight
    282.259
  • Molecular Formula
    C14H10N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (35.43 mM)
  • SMILES
    [O-][N+](=O)c1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Boschi D, et al. New potential uroselective NO-donor alpha1-antagonists. J Med Chem. 2003 Aug 14;46(17):3762-5.
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