Thymoquinone

CAS No. 490-91-5

Thymoquinone( NSC 2228 )

Catalog No. M14644 CAS No. 490-91-5

An anticancer phytochemical commonly found in black cumin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thymoquinone
  • Note
    Research use only, not for human use.
  • Brief Description
    An anticancer phytochemical commonly found in black cumin.
  • Description
    An anticancer phytochemical commonly found in black cumin; exhibits anticancer activity via numerous mechanisms of action, specifically by showing selective antioxidant and oxidant activity; directly suppresses IRAK1, strongly inhibits the production of nitric oxide (NO) and repressed NO synthase (iNOS),TNF-α, COX-2, IL-6, and IL-1β expression in LPS-activated RAW264.7 cells; significantly ameliorates disease symptoms in LPS/D-GalN-induced hepatitis and EtOH/HCl-induced gastritis mouse models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 2228
  • Pathway
    Immunology/Inflammation
  • Target
    IRAK
  • Recptor
    Bcl-2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    490-91-5
  • Formula Weight
    164.2
  • Molecular Formula
    C10H12O2
  • Purity
    >98% (HPLC)
  • Solubility
    Water: Soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    O=C1C(C)=CC(C(C(C)C)=C1)=O
  • Chemical Name
    2-isopropyl-5-methylcyclohexa-2,5-diene-1,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Khan MA, et al. Oncotarget. 2017 Apr 18. doi: 10.18632/oncotarget.17206. 2. Hossen MJ, et al. Sci Rep. 2017 Feb 20;7:42995. 3. Rukoyatkina N, et al. Cell Death Dis. 2017 Jun 29;8(6):e2898.
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