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PF-05388169
CAS No. 1604034-78-7
PF-05388169( PF 05388169 | PF05388169 )
Catalog No. M12302 CAS No. 1604034-78-7
A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePF-05388169
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective IRAK4 inhibitor with IC50 of 0.094 nM.
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DescriptionA potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM); exhibits low nM potency in LPS- and R848-induced cytokine assays (IC50=85 nM) in human PBMCs; inhibits LPS-induced TNFα in an in vivo murine model.
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In Vitro——
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In Vivo——
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SynonymsPF 05388169 | PF05388169
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PathwayImmunology/Inflammation
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TargetIRAK
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RecptorIRAK
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Research Area——
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Indication——
Chemical Information
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CAS Number1604034-78-7
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Formula Weight391.427
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Molecular FormulaC22H21N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESN#CC1=CC(N2)=C(C3=C2C4=CC(OC)=C(OCCOCCOC)C=C4N=C3)C=C1
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Chemical Name11H-Indolo[3,2-c]quinoline-9-carbonitrile, 2-methoxy-3-[2-(2-methoxyethoxy)ethoxy]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lai CY, et al. J Immunol Res. 2017;2017:7807313.
molnova catalog
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