Menin-MLL inhibitor 20( —— )

Catalog No. M28660 CAS No. 2448173-47-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Menin-MLL inhibitor 20
Note

Research use only, not for human use.
Brief Description

Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, compound 6).
Description

Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, compound 6).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

γ-secretase
Research Area

——
Indication

——

CAS Number

2448173-47-3
Formula Weight

612.72
Molecular Formula

C33H40N8O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 33.33 mg/mL (54.40 mM)
SMILES

CC(C)(C)OC(N[C@H]1CN(Cc2cc(C(Nc(cc3)ccc3-c([nH]3)cc4c3ncnc4N3CCOCC3)=O)ncc2)CCC1)=O
Chemical Name

——

1.Zhao B, et al. Identification of gamma-secretase inhibitor potency determinants on presenilin. J Biol Chem. 2008 Feb 1;283(5):2927-38.

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