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CVN424
CAS No. 2254706-21-1
CVN424( —— )
Catalog No. M28619 CAS No. 2254706-21-1
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 249 | In Stock |
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| 5MG | 236 | In Stock |
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| 10MG | 376 | In Stock |
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| 25MG | 620 | In Stock |
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| 50MG | 877 | In Stock |
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| 100MG | 1144 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCVN424
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NoteResearch use only, not for human use.
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Brief DescriptionCVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
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DescriptionCVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.(In Vivo): CVN424 is brain-penetrant and shows dose-dependent receptor occupancy that attained brain 50% of receptor occupancy at plasma concentrations of 6.0 and 7.4 ng/ml in mice and rats, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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Recptor5-HT4
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Research Area——
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Indication——
Chemical Information
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CAS Number2254706-21-1
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Formula Weight473.52
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Molecular FormulaC24H29F2N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (131.99 mM)
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SMILESCC(N(CC1)Cc(nc2N[C@H]3COCC3)c1nc2N(CC1)CCC1Oc(ccc(F)c1)c1F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.R M Eglen, et al. Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol. 1995 Aug;115(8):1387-92.
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