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TP0586532

CAS No. 2427584-96-9

TP0586532( —— )

Catalog No. M28602 CAS No. 2427584-96-9

TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TP0586532
  • Note
    Research use only, not for human use.
  • Brief Description
    TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
  • Description
    TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.(In Vitro):TP0586532 is an inhibitor of UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with an IC50 of 0.101 μM.
  • In Vitro
    TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CB1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2427584-96-9
  • Formula Weight
    460.52
  • Molecular Formula
    C26H28N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (108.57 mM)
  • SMILES
    O=C(O)CCCN1C[C@@]2([H])[C@H](C#CC3=CC=C(C4=CC(CN5C=CN=C5[C@@H](O)C)=NO4)C=C3)[C@@]2([H])C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Andreas W Herling, et al. CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E826-32.
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