TP0586532( —— )

Catalog No. M28602 CAS No. 2427584-96-9

TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

TP0586532
Note

Research use only, not for human use.
Brief Description

TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Description

TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.(In Vitro):TP0586532 is an inhibitor of UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with an IC50 of 0.101 μM.
In Vitro

TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

CB1R
Research Area

——
Indication

——

Chemical Information

CAS Number

2427584-96-9
Formula Weight

460.52
Molecular Formula

C26H28N4O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (108.57 mM)
SMILES

O=C(O)CCCN1C[C@@]2([H])[C@H](C#CC3=CC=C(C4=CC(CN5C=CN=C5[C@@H](O)C)=NO4)C=C3)[C@@]2([H])C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Andreas W Herling, et al. CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E826-32.

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