8-Hydroxy-2'-deoxyguanosine

Research use only, not for human use.

8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.

8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons.

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8-Oxo-dG | 8-Hydroxydeoxyguanosine | 8-Oxo-2'-deoxyguanosine | 2'-Deoxy-8-oxoguanosine | 8 OHdG | 8-Hydroxy-2-Deoxyguanosine

Proteasome/Ubiquitin

Endogenous Metabolite

Amino Acids and Derivatives

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88847-89-6

283.244

C10H13N5O5

>98% (HPLC)

In Vitro:?DMSO : 155 mg/mL (547.24 mM)

Nc1nc(=O)c2[nH]c(=O)n([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1

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(-20℃)

With Ice Pack

≥ 2 years