8-Hydroxy-2'-deoxyguanosine

CAS No. 88847-89-6

8-Hydroxy-2'-deoxyguanosine( 8-Oxo-dG | 8-Hydroxydeoxyguanosine | 8-Oxo-2'-deoxyguanosine | 2'-Deoxy-8-oxoguanosine | 8 OHdG | 8-Hydroxy-2-Deoxyguanosine )

Catalog No. M28576 CAS No. 88847-89-6

8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 102 In Stock
5MG 150 In Stock
10MG 239 In Stock
25MG 528 In Stock
50MG 755 In Stock
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Biological Information

  • Product Name
    8-Hydroxy-2'-deoxyguanosine
  • Note
    Research use only, not for human use.
  • Brief Description
    8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.
  • Description
    8-Oxo-dG is a good biomarker for risk assessment of various cancers and degenerative diseases.
  • In Vitro
    8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons.
  • In Vivo
    ——
  • Synonyms
    8-Oxo-dG | 8-Hydroxydeoxyguanosine | 8-Oxo-2'-deoxyguanosine | 2'-Deoxy-8-oxoguanosine | 8 OHdG | 8-Hydroxy-2-Deoxyguanosine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Amino Acids and Derivatives
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    88847-89-6
  • Formula Weight
    283.244
  • Molecular Formula
    C10H13N5O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 155 mg/mL (547.24 mM)
  • SMILES
    Nc1nc(=O)c2[nH]c(=O)n([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
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